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Preferential Signaling and Induction of Allergy-promoting Lymphokines Upon Weak Stimulation of the High Affinity IgE Receptor on Mast Cells

Mast cell degranulation and de novo cytokine production is a consequence of antigen-aggregation of the immunoglobulin E (IgE)-occupied high affinity receptor for IgE (FcɛRI). Herein, we report that lymphokines that promote allergic inflammation, like MCP-1, were potently induced at low antigen (Ag)...

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Detalles Bibliográficos
Autores principales: Gonzalez-Espinosa, Claudia, Odom, Sandra, Olivera, Ana, Hobson, J. Peyton, Martinez, Maria Eugenia Cid, Oliveira-dos-Santos, Antonio, Barra, Lillian, Spiegel, Sarah, Penninger, Josef M., Rivera, Juan
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2003
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2193904/
https://www.ncbi.nlm.nih.gov/pubmed/12782712
http://dx.doi.org/10.1084/jem.20021806