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Vaccine Immunity to Pathogenic Fungi Overcomes the Requirement for CD4 Help in Exogenous Antigen Presentation to CD8(+) T Cells: Implications for Vaccine Development in Immune-deficient Hosts

Systemic fungal infections with primary and opportunistic pathogens have become increasingly common and represent a growing health menace in patients with AIDS and other immune deficiencies. T lymphocyte immunity, in particular the CD4(+) Th 1 cells, is considered the main defense against these path...

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Detalles Bibliográficos
Autores principales: Wüthrich, Marcel, Filutowicz, Hanna I., Warner, Tom, Deepe, George S., Klein, Bruce S.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2003
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2193905/
https://www.ncbi.nlm.nih.gov/pubmed/12782709
http://dx.doi.org/10.1084/jem.20030109