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Effect of Anatomical Distribution of Mast Cells on Their Defense Function against Bacterial Infections: Demonstration Using Partially Mast Cell–deficient tg/tg Mice
Mast cells were depleted in the peritoneal cavity of WBB6F(1)-tg/tg mice that did not express a transcription factor, MITF. When acute bacterial peritonitis was induced in WBB6F(1)-+/+, WBB6F(1)-W/W (v), and WBB6F(1)-tg/tg mice, the proportion of surviving WBB6F(1)-+/+ mice was significantly higher...
| Autores principales: | , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
The Rockefeller University Press
2003
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2193916/ https://www.ncbi.nlm.nih.gov/pubmed/12771178 http://dx.doi.org/10.1084/jem.20022157 |