Delayed Cellular Maturation and Decreased Immunoglobulin κ Light Chain Production In Immature B Lymphocytes Lacking B Cell Linker Protein

B cell linker (BLNK) protein is a component of the B cell receptor (BCR) signaling pathway and BLNK(−/−) mice have a block in B lymphopoiesis at the pro-B/pre-B cell stage. To study the effect of BLNK mutation at later stages of B cell development, we introduce an innocuous transgenic BCR into BLNK(...

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Detalles Bibliográficos
Autores principales: Xu, Shengli, Lam, Kong-Peng
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2002
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2193924/
https://www.ncbi.nlm.nih.gov/pubmed/12119344
http://dx.doi.org/10.1084/jem.20020172

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2193924/
https://www.ncbi.nlm.nih.gov/pubmed/12119344
http://dx.doi.org/10.1084/jem.20020172

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