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The Immune Regulatory Function of Lymphoproliferative Double Negative T Cells In Vitro and In Vivo

Lymphoproliferative (lpr) mice, which lack functional Fas receptor expression and develop autoimmune lymphoproliferative disease, have an accumulation of T cell receptor-αβ(+)CD4(−)CD8(−) (double negative T cells [DNTC]) in the periphery. The function of the accumulating DNTC is not clear. In this s...

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Detalles Bibliográficos
Autores principales: Ford, Megan S., Young, Kevin J., Zhang, Zhuxu, Ohashi, Pamela S., Zhang, Li
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2002
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2193928/
https://www.ncbi.nlm.nih.gov/pubmed/12119351
http://dx.doi.org/10.1084/jem.20020029