Donor-type CD4(+)CD25(+) Regulatory T Cells Suppress Lethal Acute Graft-Versus-Host Disease after Allogeneic Bone Marrow Transplantation

Acute graft-versus-host disease (aGVHD) is still a major obstacle in clinical allogeneic bone marrow (BM) transplantation. CD4(+)CD25(+) regulatory T (T(reg)) cells have recently been shown to suppress proliferative responses of CD4(+)CD25(−) T cells to alloantigenic stimulation in vitro and are req...

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Detalles Bibliográficos
Autores principales: Hoffmann, Petra, Ermann, Joerg, Edinger, Matthias, Fathman, C. Garrison, Strober, Samuel
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2002
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2193938/
https://www.ncbi.nlm.nih.gov/pubmed/12163567
http://dx.doi.org/10.1084/jem.20020399

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2193938/
https://www.ncbi.nlm.nih.gov/pubmed/12163567
http://dx.doi.org/10.1084/jem.20020399

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