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Uncoupling of Proliferative Potential and Gain of Effector Function by CD8(+) T Cells Responding to Self-Antigens
Professional antigen-presenting cells (APCs) are capable of transporting self-antigens from peripheral tissues to secondary lymphoid organs where they are presented to potentially autoreactive CD8(+) T cells. In the absence of an inflammatory response, this results in immune tolerance. The presence...
| Autores principales: | , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
The Rockefeller University Press
2002
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2193940/ https://www.ncbi.nlm.nih.gov/pubmed/12163561 http://dx.doi.org/10.1084/jem.20011612 |