Genetic Dissection of SLE: SLE1 and FAS Impact Alternate Pathways Leading to Lymphoproliferative Autoimmunity

Genetic dissection of lupus pathogenesis in the NZM2410 strain has recently revealed that Sle1 is a potent locus that triggers the formation of IgG anti-histone/DNA antibodies, when expressed on the B6 background as a congenic interval. B6.lpr mice, in contrast, exhibit distinctly different cellular...

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Detalles Bibliográficos
Autores principales: Shi, Xiaoyan, Xie, Chun, Kreska, Desi, Richardson, James A., Mohan, Chandra
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2002
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2193943/
https://www.ncbi.nlm.nih.gov/pubmed/12163557
http://dx.doi.org/10.1084/jem.20010955

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2193943/
https://www.ncbi.nlm.nih.gov/pubmed/12163557
http://dx.doi.org/10.1084/jem.20010955

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