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CD36 Mediates the Innate Host Response to β-Amyloid

Accumulation of inflammatory microglia in Alzheimer's senile plaques is a hallmark of the innate response to β-amyloid fibrils and can initiate and propagate neurodegeneration characteristic of Alzheimer's disease (AD). The molecular mechanism whereby fibrillar β-amyloid activates the infl...

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Detalles Bibliográficos
Autores principales: El Khoury, Joseph B., Moore, Kathryn J., Means, Terry K., Leung, Josephine, Terada, Kinya, Toft, Michelle, Freeman, Mason W., Luster, Andrew D.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2003
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2193948/
https://www.ncbi.nlm.nih.gov/pubmed/12796468
http://dx.doi.org/10.1084/jem.20021546