Bruton's Tyrosine Kinase Is Required For Lipopolysaccharide-induced Tumor Necrosis Factor α Production

Lipopolysaccharide (LPS), a product of Gram-negative bacteria, is potent mediator of tumor necrosis factor (TNF)α production by myeloid/macrophage cells. Inhibitors capable of blocking the signaling events that result in TNFα production could provide useful therapeutics for treating septic shock and...

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Detalles Bibliográficos
Autores principales: Horwood, Nicole J., Mahon, Tara, McDaid, John P., Campbell, Jamie, Mano, Hiroyuki, Brennan, Fionula M., Webster, David, Foxwell, Brian M.J.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2003
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2193950/
https://www.ncbi.nlm.nih.gov/pubmed/12810683
http://dx.doi.org/10.1084/jem.20021845

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2193950/
https://www.ncbi.nlm.nih.gov/pubmed/12810683
http://dx.doi.org/10.1084/jem.20021845

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