Unraveling a Revealing Paradox: Why Major Histocompatibility Complex I–signaled Thymocytes “Paradoxically” Appear as CD4(+)8(lo) Transitional Cells During Positive Selection of CD8(+) T Cells

The mechanism by which T cell receptor specificity determines the outcome of the CD4/CD8 lineage decision in the thymus is not known. An important clue is the fact that major histocompatibility complex (MHC)-I–signaled thymocytes paradoxically appear as CD4(+)8(lo) transitional cells during their di...

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Detalles Bibliográficos
Autores principales: Bosselut, Remy, Guinter, Terry I., Sharrow, Susan O., Singer, Alfred
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2003
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2193957/
https://www.ncbi.nlm.nih.gov/pubmed/12810689
http://dx.doi.org/10.1084/jem.20030170

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2193957/
https://www.ncbi.nlm.nih.gov/pubmed/12810689
http://dx.doi.org/10.1084/jem.20030170

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