Tumors Acquire Inhibitor of Apoptosis Protein (IAP)-mediated Apoptosis Resistance through Altered Specificity of Cytosolic Proteolysis

Many tumors overexpress members of the inhibitor of apoptosis protein (IAP) family. IAPs contribute to tumor cell apoptosis resistance by the inhibition of caspases, and are degraded by the proteasome to allow further progression of apoptosis. Here we show that tumor cells can alter the specificity...

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Detalles Bibliográficos
Autores principales: Hong, Xu, Lei, Lu, Glas, Rickard
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2003
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2193958/
https://www.ncbi.nlm.nih.gov/pubmed/12810691
http://dx.doi.org/10.1084/jem.20020801

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2193958/
https://www.ncbi.nlm.nih.gov/pubmed/12810691
http://dx.doi.org/10.1084/jem.20020801

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