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Normal Incidence of Diabetes in NOD Mice Tolerant to Glutamic Acid Decarboxylase
Experiments in nonobese diabetic (NOD) mice that lacked expression of glutamic acid decarboxylase (GAD) in β cells have suggested that GAD represents an autoantigen essential for initiating and maintaining the diabetogenic immune response. Several attempts of inducing GAD-specific recessive toleranc...
Autores principales: | , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2003
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2193961/ https://www.ncbi.nlm.nih.gov/pubmed/12796471 http://dx.doi.org/10.1084/jem.20030215 |