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Normal Incidence of Diabetes in NOD Mice Tolerant to Glutamic Acid Decarboxylase

Experiments in nonobese diabetic (NOD) mice that lacked expression of glutamic acid decarboxylase (GAD) in β cells have suggested that GAD represents an autoantigen essential for initiating and maintaining the diabetogenic immune response. Several attempts of inducing GAD-specific recessive toleranc...

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Detalles Bibliográficos
Autores principales: Jaeckel, Elmar, Klein, Ludger, Martin-Orozco, Natalia, von Boehmer, Harald
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2003
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2193961/
https://www.ncbi.nlm.nih.gov/pubmed/12796471
http://dx.doi.org/10.1084/jem.20030215