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Visualization of the Genesis and Fate of Isotype-switched B Cells during a Primary Immune Response
The life history of isotype-switched B cells is unclear, in part, because of an inability to detect rare antigen-specific B cells at early times during the immune response. To address this issue, a small population of B cells carrying targeted antibody transgenes capable of class switching was monit...
Autores principales: | , , , , , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2003
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2193962/ https://www.ncbi.nlm.nih.gov/pubmed/12796466 http://dx.doi.org/10.1084/jem.20012065 |