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Visualization of the Genesis and Fate of Isotype-switched B Cells during a Primary Immune Response

The life history of isotype-switched B cells is unclear, in part, because of an inability to detect rare antigen-specific B cells at early times during the immune response. To address this issue, a small population of B cells carrying targeted antibody transgenes capable of class switching was monit...

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Detalles Bibliográficos
Autores principales: Pape, Kathryn A., Kouskoff, Valerie, Nemazee, David, Tang, H. Lucy, Cyster, Jason G., Tze, Lina E., Hippen, Keli L., Behrens, Timothy W., Jenkins, Marc K.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2003
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2193962/
https://www.ncbi.nlm.nih.gov/pubmed/12796466
http://dx.doi.org/10.1084/jem.20012065