Constitutive Expression of AID Leads to Tumorigenesis

Genome stability is regulated by the balance between efficiencies of the repair machinery and genetic alterations such as mutations and chromosomal rearrangements. It has been postulated that deregulation of class switch recombination (CSR) and somatic hypermutation (SHM), which modify the immunoglo...

Descripción completa

Detalles Bibliográficos
Autores principales: Okazaki, Il-mi, Hiai, Hiroshi, Kakazu, Naoki, Yamada, Shuichi, Muramatsu, Masamichi, Kinoshita, Kazuo, Honjo, Tasuku
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2003
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2193972/
https://www.ncbi.nlm.nih.gov/pubmed/12732658
http://dx.doi.org/10.1084/jem.20030275

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2193972/
https://www.ncbi.nlm.nih.gov/pubmed/12732658
http://dx.doi.org/10.1084/jem.20030275

Ejemplares similares