In Vivo Activation of cAMP Signaling Induces Growth Arrest and Differentiation in Acute Promyelocytic Leukemia

Differentiation therapy for acute myeloid leukemia uses transcriptional modulators to reprogram cancer cells. The most relevant clinical example is acute promyelocytic leukemia (APL), which responds dramatically to either retinoic acid (RA) or arsenic trioxide (As(2)O(3)). In many myeloid leukemia c...

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Detalles Bibliográficos
Autores principales: Guillemin, Marie-Claude, Raffoux, Emmanuel, Vitoux, Dominique, Kogan, Scott, Soilihi, Hassane, Lallemand-Breitenbach, Valérie, Zhu, Jun, Janin, Anne, Daniel, Marie-Thérèse, Gourmel, Bernard, Degos, Laurent, Dombret, Hervé, Lanotte, Michel, de Thé, Hugues
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2002
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2193985/
https://www.ncbi.nlm.nih.gov/pubmed/12438428
http://dx.doi.org/10.1084/jem.20021129

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2193985/
https://www.ncbi.nlm.nih.gov/pubmed/12438428
http://dx.doi.org/10.1084/jem.20021129

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