Crosstalk Between BCR/ABL Oncoprotein and CXCR4 Signaling through a Src Family Kinase in Human Leukemia Cells

Stromal-derived factor (SDF)-1 and its G protein–coupled receptor, CXCR4, regulate stem/progenitor cell migration and retention in the marrow and are required for hematopoiesis. We show here an interaction between CXCR4 and the Src-related kinase, Lyn, in normal progenitors. We demonstrate that CXCR...

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Detalles Bibliográficos
Autores principales: Ptasznik, Andrzej, Urbanowska, Elzbieta, Chinta, Suneetha, Costa, Melinda A., Katz, Benjamin A., Stanislaus, Marisha A., Demir, Gokhan, Linnekin, Diana, Pan, Zhixing K., Gewirtz, Alan M.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2002
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2193994/
https://www.ncbi.nlm.nih.gov/pubmed/12208881
http://dx.doi.org/10.1084/jem.20020519

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2193994/
https://www.ncbi.nlm.nih.gov/pubmed/12208881
http://dx.doi.org/10.1084/jem.20020519

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