Activation and Differentiation of Autoreactive B-1 Cells by Interleukin 10 Induce Autoimmune Hemolytic Anemia in Fas-deficient Antierythrocyte Immunoglobulin Transgenic Mice

The Fas (CD95) gene is among critical genetic factors in some autoimmune diseases, which are characterized by autoantibody (autoAb) productions. In mice, mutations in the Fas gene cause lymphoproliferation (lpr) which predominantly develops glomerulonephritis, whereas the mutations in human cause au...

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Detalles Bibliográficos
Autores principales: Watanabe, Norihiko, Ikuta, Koichi, Nisitani, Sazuku, Chiba, Tsutomu, Honjo, Tasuku
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2002
Materias:
Brief Definitive Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2194013/
https://www.ncbi.nlm.nih.gov/pubmed/12093879
http://dx.doi.org/10.1084/jem.20011519

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2194013/
https://www.ncbi.nlm.nih.gov/pubmed/12093879
http://dx.doi.org/10.1084/jem.20011519

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