Constitutive Expression of the B7h Ligand for Inducible Costimulator on Naive B Cells Is Extinguished after Activation by Distinct B Cell Receptor and Interleukin 4 Receptor–mediated Pathways and Can Be Rescued by CD40 Signaling

The recently described ligand–receptor pair, B7h–inducible costimulator (ICOS), is critical for germinal center formation and antibody responses. In contrast to the induced expression of the related costimulatory ligands B7.1 and B7.2, B7h is constitutively expressed on naive B cells and is surprisi...

Descripción completa

Detalles Bibliográficos
Autores principales: Liang, Linda, Porter, Evelyn M., Sha, William C.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2002
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2194020/
https://www.ncbi.nlm.nih.gov/pubmed/12093874
http://dx.doi.org/10.1084/jem.20020298

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2194020/
https://www.ncbi.nlm.nih.gov/pubmed/12093874
http://dx.doi.org/10.1084/jem.20020298

Ejemplares similares