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CD103 Expression Is Required for Destruction of Pancreatic Islet Allografts by CD8(+) T Cells

The mechanisms by which CD8 effector populations interact with epithelial layers is a poorly defined aspect of adaptive immunity. Recognition that CD8 effectors have the capacity to express CD103, an integrin directed to the epithelial cell-specific ligand E-cadherin, potentially provides insight in...

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Detalles Bibliográficos
Autores principales: Feng, Ye, Wang, Donghua, Yuan, Rongwen, Parker, Christina M., Farber, Donna L., Hadley, Gregg A.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2002
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2194029/
https://www.ncbi.nlm.nih.gov/pubmed/12370250
http://dx.doi.org/10.1084/jem.20020178