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Resolvins: A Family of Bioactive Products of Omega-3 Fatty Acid Transformation Circuits Initiated by Aspirin Treatment that Counter Proinflammation Signals

Aspirin (ASA) is unique among current therapies because it acetylates cyclooxygenase (COX)-2 enabling the biosynthesis of R-containing precursors of endogenous antiinflammatory mediators. Here, we report that lipidomic analysis of exudates obtained in the resolution phase from mice treated with ASA...

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Detalles Bibliográficos
Autores principales: Serhan, Charles N., Hong, Song, Gronert, Karsten, Colgan, Sean P., Devchand, Pallavi R., Mirick, Gudrun, Moussignac, Rose-Laure
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2002
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2194036/
https://www.ncbi.nlm.nih.gov/pubmed/12391014
http://dx.doi.org/10.1084/jem.20020760