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Nucleolin as Activator of Human Papillomavirus Type 18 Oncogene Transcription in Cervical Cancer

High risk human papillomaviruses (HPVs) are central to the development of cervical cancer and the deregulated expression of high risk HPV oncogenes is a critical event in this process. Here, we find that the cell protein nucleolin binds in a sequence-specific manner to the HPV18 enhancer. The DNA bi...

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Detalles Bibliográficos
Autores principales: Grinstein, Edgar, Wernet, Peter, Snijders, Peter J.F., Rösl, Frank, Weinert, Inge, Jia, Wentao, Kraft, Regine, Schewe, Christiane, Schwabe, Michael, Hauptmann, Steffen, Dietel, Manfred, Meijer, Chris J.L.M., Royer, Hans-Dieter
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2002
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2194043/
https://www.ncbi.nlm.nih.gov/pubmed/12391018
http://dx.doi.org/10.1084/jem.20011053