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Intracrine Cysteinyl Leukotriene Receptor–mediated Signaling of Eosinophil Vesicular Transport–mediated Interleukin-4 Secretion

We investigated whether cysteinyl leukotrienes (cysLT) are intracrine signal transducers that regulate human eosinophil degranulation mechanisms. Interleukin (IL)-16, eotaxin, and RANTES stimulate vesicular transport–mediated release of preformed, granule-derived IL-4 and RANTES from eosinophils and...

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Detalles Bibliográficos
Autores principales: Bandeira-Melo, Christianne, Woods, Lesley J., Phoofolo, Mojabeng, Weller, Peter F.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2002
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2194050/
https://www.ncbi.nlm.nih.gov/pubmed/12235216
http://dx.doi.org/10.1084/jem.20020516