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The Proliferative Capacity of Individual Naive CD4(+)T Cells Is Amplified by Prolonged T Cell Antigen Receptor Triggering

Strong antigenic encounter by T cells rapidly induces immunological synapse formation and surface T cell receptor (TCR) downregulation. Although surface TCR expression can remain low for several days, T cells can still sustain antigenic signaling. It has been unclear whether prolonged antigenic sign...

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Detalles Bibliográficos
Autores principales:	Schrum, Adam G., Turka, Laurence A.
Formato:	Texto
Lenguaje:	English
Publicado:	The Rockefeller University Press 2002
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2194051/ https://www.ncbi.nlm.nih.gov/pubmed/12235212 http://dx.doi.org/10.1084/jem.20020158

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