A Crucial Role for the p110δ Subunit of Phosphatidylinositol 3-Kinase in B Cell Development and Activation

Mice lacking the p110δ catalytic subunit of phosphatidylinositol 3-kinase have reduced numbers of B1 and marginal zone B cells, reduced levels of serum immunoglobulins, respond poorly to immunization with type II thymus-independent antigen, and are defective in their primary and secondary responses...

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Detalles Bibliográficos
Autores principales: Clayton, Elizabeth, Bardi, Giuseppe, Bell, Sarah E., Chantry, David, Downes, C. Peter, Gray, Alexander, Humphries, Lisa A., Rawlings, David, Reynolds, Helen, Vigorito, Elena, Turner, Martin
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2002
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2194055/
https://www.ncbi.nlm.nih.gov/pubmed/12235209
http://dx.doi.org/10.1084/jem.20020805

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2194055/
https://www.ncbi.nlm.nih.gov/pubmed/12235209
http://dx.doi.org/10.1084/jem.20020805

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