XIAP-mediated Caspase Inhibition in Hodgkin's Lymphoma–derived B Cells

The malignant Hodgkin and Reed-Sternberg cells of Hodgkin's lymphoma (HL) and HL-derived B cell lines were previously shown to be resistant to different apoptotic stimuli. We show here that cytochrome c fails to stimulate caspases-9 and -3 activation in cytosolic extracts of HL-derived B cells,...

Descripción completa

Detalles Bibliográficos
Autores principales: Kashkar, Hamid, Haefs, Christiane, Shin, Hwain, Hamilton-Dutoit, Stephen J., Salvesen, Guy S., Krönke, Martin, Jürgensmeier, Juliane M.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2003
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2194071/
https://www.ncbi.nlm.nih.gov/pubmed/12874265
http://dx.doi.org/10.1084/jem.20021279

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2194071/
https://www.ncbi.nlm.nih.gov/pubmed/12874265
http://dx.doi.org/10.1084/jem.20021279

Ejemplares similares