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XIAP-mediated Caspase Inhibition in Hodgkin's Lymphoma–derived B Cells

The malignant Hodgkin and Reed-Sternberg cells of Hodgkin's lymphoma (HL) and HL-derived B cell lines were previously shown to be resistant to different apoptotic stimuli. We show here that cytochrome c fails to stimulate caspases-9 and -3 activation in cytosolic extracts of HL-derived B cells,...

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Detalles Bibliográficos
Autores principales:	Kashkar, Hamid, Haefs, Christiane, Shin, Hwain, Hamilton-Dutoit, Stephen J., Salvesen, Guy S., Krönke, Martin, Jürgensmeier, Juliane M.
Formato:	Texto
Lenguaje:	English
Publicado:	The Rockefeller University Press 2003
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2194071/ https://www.ncbi.nlm.nih.gov/pubmed/12874265 http://dx.doi.org/10.1084/jem.20021279

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