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Direct Expansion of Functional CD25(+) CD4(+) Regulatory T Cells by Antigen-processing Dendritic Cells

An important pathway for immune tolerance is provided by thymic-derived CD25(+) CD4(+) T cells that suppress other CD25(−) autoimmune disease–inducing T cells. The antigen-presenting cell (APC) requirements for the control of CD25(+) CD4(+) suppressor T cells remain to be identified, hampering their...

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Detalles Bibliográficos
Autores principales: Yamazaki, Sayuri, Iyoda, Tomonori, Tarbell, Kristin, Olson, Kara, Velinzon, Klara, Inaba, Kayo, Steinman, Ralph M.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2003
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2194081/
https://www.ncbi.nlm.nih.gov/pubmed/12874257
http://dx.doi.org/10.1084/jem.20030422