Differential Antigen Presentation Regulates the Changing Patterns of CD8(+) T Cell Immunodominance in Primary and Secondary Influenza Virus Infections

The specificity of CD8(+) T cell responses can vary dramatically between primary and secondary infections. For example, NP(366–374)/D(b)- and PA(224–233)/D(b)-specific CD8(+) T cells respond in approximately equal numbers to a primary influenza virus infection in C57BL/6 mice, whereas NP(366–374)/D(...

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Detalles Bibliográficos
Autores principales: Crowe, Sherry R., Turner, Stephen J., Miller, Shannon C., Roberts, Alan D., Rappolo, Rachel A., Doherty, Peter C., Ely, Kenneth H., Woodland, David L.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2003
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2194086/
https://www.ncbi.nlm.nih.gov/pubmed/12885871
http://dx.doi.org/10.1084/jem.20022151

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2194086/
https://www.ncbi.nlm.nih.gov/pubmed/12885871
http://dx.doi.org/10.1084/jem.20022151

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