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Peroxisome Proliferator–activated Receptors α and γ Down-regulate Allergic Inflammation and Eosinophil Activation

Allergic asthma is characterized by airway hyperresponsiveness, eosinophilia, and mucus accumulation and is associated with increased IgE concentrations. We demonstrate here that peroxisome proliferator–activated receptors (PPARs), PPAR-α and PPAR-γ, which have been shown recently to be involved in...

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Detalles Bibliográficos
Autores principales: Woerly, Gaetane, Honda, Kohei, Loyens, Marc, Papin, Jean-Paul, Auwerx, Johan, Staels, Bart, Capron, Monique, Dombrowicz, David
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2003
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2194090/
https://www.ncbi.nlm.nih.gov/pubmed/12900517
http://dx.doi.org/10.1084/jem.20021384