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CSF-induced and HIV-1–mediated Distinct Regulation of Hck and C/EBPβ Represent a Heterogeneous Susceptibility of Monocyte-derived Macrophages to M-tropic HIV-1 Infection

Granulocyte/macrophage colony-stimulating factor (GM-CSF)–induced monocyte-derived macrophages (GM-MΦ) are permissive to M-tropic HIV-1 entry, but inhibit viral replication at posttranscriptional and translational levels, whereas M-CSF-induced macrophages (M-MΦ) produce a large amount of HIV-1. M-MΦ...

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Detalles Bibliográficos
Autores principales: Komuro, Iwao, Yokota, Yasuko, Yasuda, Sachiko, Iwamoto, Aikichi, Kagawa, Kiyoko S.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2003
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2194092/
https://www.ncbi.nlm.nih.gov/pubmed/12900520
http://dx.doi.org/10.1084/jem.20022018