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A Monoclonal Antibody to the α2 Domain of Murine Major Histocompatibility Complex Class I that Specifically Kills Activated Lymphocytes and Blocks Liver Damage in the Concanavalin A Hepatitis Model

We earlier found that a rat monoclonal antibody (mAb) RE2 can induce rapid death of murine activated, but not resting, lymphocytes and lymphocyte cell lines, in a complement-independent manner, a cell death differing from typical apoptosis or necrosis. We here found that this cell death is independe...

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Detalles Bibliográficos
Autores principales: Matsuoka, Shuji, Tsurui, Hiromichi, Abe, Masaaki, Terashima, Kazuo, Nakamura, Kazuhiro, Hamano, Yoshitomo, Ohtsuji, Mareki, Honma, Nakayuki, Serizawa, Isao, Ishii, Yasuyuki, Takiguchi, Masafumi, Hirose, Sachiko, Shirai, Toshikazu
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2003
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2194093/
https://www.ncbi.nlm.nih.gov/pubmed/12885869
http://dx.doi.org/10.1084/jem.20021301