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The B Cell Antigen Receptor Controls Integrin Activity through Btk and PLCγ2

Integrin-mediated adhesion and B cell antigen receptor (BCR) signaling play a critical role in B cell development and function, including antigen-specific B cell differentiation. Here we show that the BCR controls integrin α4β1 (VLA-4)-mediated adhesion of B cells to vascular cell adhesion molecule-...

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Detalles Bibliográficos
Autores principales: Spaargaren, Marcel, Beuling, Esther A., Rurup, Mette L., Meijer, Helen P., Klok, Melanie D., Middendorp, Sabine, Hendriks, Rudolf W., Pals, Steven T.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2003
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2194118/
https://www.ncbi.nlm.nih.gov/pubmed/14610042
http://dx.doi.org/10.1084/jem.20011866