Cargando…
The B Cell Antigen Receptor Controls Integrin Activity through Btk and PLCγ2
Integrin-mediated adhesion and B cell antigen receptor (BCR) signaling play a critical role in B cell development and function, including antigen-specific B cell differentiation. Here we show that the BCR controls integrin α4β1 (VLA-4)-mediated adhesion of B cells to vascular cell adhesion molecule-...
Autores principales: | Spaargaren, Marcel, Beuling, Esther A., Rurup, Mette L., Meijer, Helen P., Klok, Melanie D., Middendorp, Sabine, Hendriks, Rudolf W., Pals, Steven T. |
---|---|
Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2003
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2194118/ https://www.ncbi.nlm.nih.gov/pubmed/14610042 http://dx.doi.org/10.1084/jem.20011866 |
Ejemplares similares
-
Regulation of Cytokine Signaling by B Cell Antigen Receptor and Cd40-Controlled Expression of Heparan Sulfate Proteoglycans
por: van der Voort, Robbert, et al.
Publicado: (2000) -
Role of the Btk-PLCγ2 Signaling Pathway in the Bone Destruction of Apical Periodontitis
por: Wang, Lina, et al.
Publicado: (2019) -
Using high-sensitivity sequencing for the detection of mutations in BTK and PLCγ2 genes in cellular and cell-free DNA and correlation with progression in patients treated with BTK inhibitors
por: Albitar, Adam, et al.
Publicado: (2017) -
Integrin Signaling Shaping BTK-Inhibitor Resistance
por: Polcik, Laura, et al.
Publicado: (2022) -
The small FOXP1 isoform predominantly expressed in activated B cell-like diffuse large B-cell lymphoma and full-length FOXP1 exert similar oncogenic and transcriptional activity in human B cells
por: van Keimpema, Martine, et al.
Publicado: (2017)