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Complementary Signaling through flt3 and Interleukin-7 Receptor α Is Indispensable for Fetal and Adult B Cell Genesis

Extensive studies of mice deficient in one or several cytokine receptors have failed to support an indispensable role of cytokines in development of multiple blood cell lineages. Whereas B1 B cells and Igs are sustained at normal levels throughout life of mice deficient in IL-7, IL-7Rα, common cytok...

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Detalles Bibliográficos
Autores principales: Sitnicka, Ewa, Brakebusch, Cord, Martensson, Inga-Lill, Svensson, Marcus, Agace, William W., Sigvardsson, Mikael, Buza-Vidas, Natalija, Bryder, David, M.Cilio, Corrado, Ahlenius, Henrik, Maraskovsky, Eugene, Peschon, Jacques J., Jacobsen, Sten Eirik W.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2003
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2194121/
https://www.ncbi.nlm.nih.gov/pubmed/14610045
http://dx.doi.org/10.1084/jem.20031152