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The Pattern Recognition Receptor (RAGE) Is a Counterreceptor for Leukocyte Integrins: A Novel Pathway for Inflammatory Cell Recruitment

The pattern recognition receptor, RAGE (receptor for advanced glycation endproducts), propagates cellular dysfunction in several inflammatory disorders and diabetes. Here we show that RAGE functions as an endothelial adhesion receptor promoting leukocyte recruitment. In an animal model of thioglycol...

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Detalles Bibliográficos
Autores principales: Chavakis, Triantafyllos, Bierhaus, Angelika, Al-Fakhri, Nadia, Schneider, Darius, Witte, Steffen, Linn, Thomas, Nagashima, Mariko, Morser, John, Arnold, Bernd, Preissner, Klaus T., Nawroth, Peter P.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2003
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2194124/
https://www.ncbi.nlm.nih.gov/pubmed/14623906
http://dx.doi.org/10.1084/jem.20030800