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IL-4–Stat6 Signaling Induces Tristetraprolin Expression and Inhibits TNF-α Production in Mast Cells

Increasing evidence has revealed that mast cell–derived tumor necrosis factor α (TNF-α) plays a critical role in a number of inflammatory responses by recruiting inflammatory leukocytes. In this paper, we investigated the regulatory role of interleukin 4 (IL-4) in TNF-α production in mast cells. IL-...

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Detalles Bibliográficos
Autores principales: Suzuki, Kotaro, Nakajima, Hiroshi, Ikeda, Kei, Maezawa, Yuko, Suto, Akira, Takatori, Hiroaki, Saito, Yasushi, Iwamoto, Itsuo
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2003
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2194141/
https://www.ncbi.nlm.nih.gov/pubmed/14638848
http://dx.doi.org/10.1084/jem.20031701