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Activation of Transforming Growth Factor β by Malaria Parasite-derived Metalloproteinases and a Thrombospondin-like Molecule

Much of the pathology of malaria is mediated by inflammatory cytokines (such as interleukin 12, interferon γ, and tumor necrosis factor α), which are part of the immune response that kills the parasite. The antiinflammatory cytokine transforming growth factor (TGF)-β plays a crucial role in preventi...

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Detalles Bibliográficos
Autores principales: Omer, Fakhreldin M., de Souza, J. Brian, Corran, Patrick H., Sultan, Ali A., Riley, Eleanor M.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2003
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2194152/
https://www.ncbi.nlm.nih.gov/pubmed/14676296
http://dx.doi.org/10.1084/jem.20030713