Tuberculosis Toxin Blocking Phagosome Maturation Inhibits a Novel Ca(2+)/Calmodulin-PI3K hVPS34 Cascade

The capacity of Mycobacterium tuberculosis to infect latently over one billion people and cause two million fatalities annually rests with its ability to block phagosomal maturation into the phagolysosome in infected macrophages. Here we describe how M. tuberculosis toxin lipoarabinomannan (LAM) cau...

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Detalles Bibliográficos
Autores principales: Vergne, Isabelle, Chua, Jennifer, Deretic, Vojo
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2003
Materias:
Brief Definitive Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2194170/
https://www.ncbi.nlm.nih.gov/pubmed/12925680
http://dx.doi.org/10.1084/jem.20030527

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2194170/
https://www.ncbi.nlm.nih.gov/pubmed/12925680
http://dx.doi.org/10.1084/jem.20030527

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