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Tuberculosis Toxin Blocking Phagosome Maturation Inhibits a Novel Ca(2+)/Calmodulin-PI3K hVPS34 Cascade
The capacity of Mycobacterium tuberculosis to infect latently over one billion people and cause two million fatalities annually rests with its ability to block phagosomal maturation into the phagolysosome in infected macrophages. Here we describe how M. tuberculosis toxin lipoarabinomannan (LAM) cau...
| Autores principales: | , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
The Rockefeller University Press
2003
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2194170/ https://www.ncbi.nlm.nih.gov/pubmed/12925680 http://dx.doi.org/10.1084/jem.20030527 |