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Arf6 and Phosphoinositol-4-Phosphate-5-Kinase Activities Permit Bypass of the Rac1 Requirement for β(1) Integrin–mediated Bacterial Uptake

Efficient entry of the bacterium Yersinia pseudotuberculosis into mammalian cells requires the binding of the bacterial invasin protein to β1 integrin receptors and the activation of the small GTPase Rac1. We report here that this Rac1-dependent pathway involves recruitment of phosphoinositol-4-phos...

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Detalles Bibliográficos
Autores principales: Wong, Ka-Wing, Isberg, Ralph R.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2003
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2194175/
https://www.ncbi.nlm.nih.gov/pubmed/12925676
http://dx.doi.org/10.1084/jem.20021363