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Arf6 and Phosphoinositol-4-Phosphate-5-Kinase Activities Permit Bypass of the Rac1 Requirement for β(1) Integrin–mediated Bacterial Uptake
Efficient entry of the bacterium Yersinia pseudotuberculosis into mammalian cells requires the binding of the bacterial invasin protein to β1 integrin receptors and the activation of the small GTPase Rac1. We report here that this Rac1-dependent pathway involves recruitment of phosphoinositol-4-phos...
Autores principales: | Wong, Ka-Wing, Isberg, Ralph R. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2003
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2194175/ https://www.ncbi.nlm.nih.gov/pubmed/12925676 http://dx.doi.org/10.1084/jem.20021363 |
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