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Coupling Between B Cell Receptor and Phospholipase C-γ2 Is Essential for Mature B Cell Development

Two signaling pathways known to be essential for progression from immature to mature B cells are BAFF receptor (BAFF-R) and the B cell receptor (BCR). Here, we first show that phospholipase C (PLC)-γ2 is required for a BAFF-R–mediated survival signal. Then, we have examined the question of whether t...

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Detalles Bibliográficos
Autores principales: Hikida, Masaki, Johmura, Sachiko, Hashimoto, Ari, Takezaki, Mayuko, Kurosaki, Tomohiro
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2003
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2194178/
https://www.ncbi.nlm.nih.gov/pubmed/12913095
http://dx.doi.org/10.1084/jem.20030280