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Plasmin Activates the Lymphangiogenic Growth Factors VEGF-C and VEGF-D

Vascular endothelial growth factor (VEGF) C and VEGF-D stimulate lymphangiogenesis and angiogenesis in tissues and tumors by activating the endothelial cell surface receptor tyrosine kinases VEGF receptor (VEGFR) 2 and VEGFR-3. These growth factors are secreted as full-length inactive forms consisti...

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Detalles Bibliográficos
Autores principales: McColl, Bradley K., Baldwin, Megan E., Roufail, Sally, Freeman, Craig, Moritz, Robert L., Simpson, Richard J., Alitalo, Kari, Stacker, Steven A., Achen, Marc G.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2003
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2194198/
https://www.ncbi.nlm.nih.gov/pubmed/12963694
http://dx.doi.org/10.1084/jem.20030361