Restoration of CD28 Expression in CD28(−) CD8(+) Memory Effector T Cells Reconstitutes Antigen-induced IL-2 Production

The control of many persistent viral infections by Ag-specific cytolytic CD8(+) T cells requires a concurrent virus-specific CD4(+) Th cell response. This reflects in part a requirement of activated effector CD8(+) T cells for paracrine IL-2 production as a growth and survival factor. In human CMV a...

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Detalles Bibliográficos
Autores principales: Topp, Max S., Riddell, Stanley R., Akatsuka, Yoshiki, Jensen, Michael C., Blattman, Joseph N., Greenberg, Philip D.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2003
Materias:
Brief Definitive Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2194206/
https://www.ncbi.nlm.nih.gov/pubmed/12963692
http://dx.doi.org/10.1084/jem.20021288

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2194206/
https://www.ncbi.nlm.nih.gov/pubmed/12963692
http://dx.doi.org/10.1084/jem.20021288

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