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The Proinflammatory Mediators C3a and C5a Are Essential for Liver Regeneration
Complement has been implicated in liver repair after toxic injury. Here, we demonstrate that complement components are essential for liver regeneration, and mediate their effect by interacting with key signaling networks that promote hepatocyte proliferation. C3- or C5-deficient mice exhibited high...
| Autores principales: | , , , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
The Rockefeller University Press
2003
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2194207/ https://www.ncbi.nlm.nih.gov/pubmed/12975457 http://dx.doi.org/10.1084/jem.20030374 |