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The Strength of Persistent Antigenic Stimulation Modulates Adaptive Tolerance in Peripheral CD4(+) T Cells
The quantitative adaptation of receptor thresholds allows cells to tailor their responses to changes in ambient ligand concentration in many biological systems. Such a cell-intrinsic calibration of T cell receptor (TCR) sensitivity could be involved in regulating responses to autoantigens, but this...
| Autores principales: | , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
The Rockefeller University Press
2003
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2194218/ https://www.ncbi.nlm.nih.gov/pubmed/14530379 http://dx.doi.org/10.1084/jem.20030913 |