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The Strength of Persistent Antigenic Stimulation Modulates Adaptive Tolerance in Peripheral CD4(+) T Cells

The quantitative adaptation of receptor thresholds allows cells to tailor their responses to changes in ambient ligand concentration in many biological systems. Such a cell-intrinsic calibration of T cell receptor (TCR) sensitivity could be involved in regulating responses to autoantigens, but this...

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Detalles Bibliográficos
Autores principales:	Singh, Nevil J., Schwartz, Ronald H.
Formato:	Texto
Lenguaje:	English
Publicado:	The Rockefeller University Press 2003
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2194218/ https://www.ncbi.nlm.nih.gov/pubmed/14530379 http://dx.doi.org/10.1084/jem.20030913

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