Loss of the Pro-Apoptotic BH3-only Bcl-2 Family Member Bim Inhibits BCR Stimulation–induced Apoptosis and Deletion of Autoreactive B Cells

During development, the stochastic process assembling the genes encoding antigen receptors invariably generates B and T lymphocytes that can recognize self-antigens. Several mechanisms have evolved to prevent the activation of these cells and the concomitant development of autoimmune disease. One su...

Descripción completa

Detalles Bibliográficos
Autores principales: Enders, Anselm, Bouillet, Philippe, Puthalakath, Hamsa, Xu, Yuekang, Tarlinton, David M., Strasser, Andreas
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2003
Materias:
Brief Definitive Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2194219/
https://www.ncbi.nlm.nih.gov/pubmed/14517273
http://dx.doi.org/10.1084/jem.20030411

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2194219/
https://www.ncbi.nlm.nih.gov/pubmed/14517273
http://dx.doi.org/10.1084/jem.20030411

Ejemplares similares