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Thrombospondin 1 Is an Autocrine Negative Regulator of Human Dendritic Cell Activation
Thrombospondin 1 (TSP) elicits potent antiinflammatory activities in vivo, as evidenced by persistent, multiorgan inflammation in TSP null mice. Herein, we report that DCs represent an abundant source of TSP at steady state and during activation. Human monocyte-derived immature dendritic cells (iDCs...
Autores principales: | Doyen, Virginie, Rubio, Manuel, Braun, Deborah, Nakajima, Toshiaru, Abe, Jun, Saito, Hirohisa, Delespesse, Guy, Sarfati, Marika |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2003
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2194231/ https://www.ncbi.nlm.nih.gov/pubmed/14568985 http://dx.doi.org/10.1084/jem.20030705 |
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